Changes that a lady might notice at home, for example, would include a new lump. That goes into the lady checking herself, which we still feel is important. She feels something that's new to her, if she sees any changes as far as the color of the breast, meaning if she ever wakes up someday and it looks like scalding water went to her breast causing a lot of redness, that ought to be evaluated. You just don't assume it's an infection, because there's a certain type of cancer called inflammatory breast cancer that can present that way. Other findings might be bloody nipple discharge. Another finding might be skin inversion. Anywhere on the skin, if it's all of sudden dimpled, or if the nipple's now inverted where it's sunken in, and that's new to that patient, needs to evaluated.