Migraines most commonly start prior to the age of 40, although they can occur at any age, even children have been reported have migraines as young as four years old. But they are more common in young females, and there is a large association between migraines and hormones, and this can be seen as we enter puberty, where migraines become more common in girls than in boys around that time. And a lot of women report that their first migraine attack did occur around the time of their first menstrual period. This pattern of migraines being more common in girls than in boys persists throughout life and its about three times more common in women than in men. Migraines can be associated with menstrual periods and when this happens it's called menstrual migraine. And during pregnancy, migraines can often times settle down. And later in life, such as during perimenopause, as hormone levels fluctuate, migraines can actually get a little worse. And then later during menopause as hormone levels settle down, migraines often settle down as well.